- Science
- Global
One DNA letter can trigger complete sex reversal
- April 9, 2026 at 9:00 AM
- 6 views
Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development in mice. In the new study, published in Nature Communications, a single-letter insertion in a non-coding regulatory region caused XX mice, which would normally develop as females, to develop instead as males with testis and male genitalia.
Originally published at Phys.org