Molecular glue could hijack cells' natural machinery to help treat diseases

Proteins do most of the work in our body's cells. But when a protein is too active or does not function properly, it can lead to disease or other health problems. Researchers from the University of Toronto have discovered a molecule, CLEO4-88, that acts as a "molecular glue," binding together two proteins to inactivate one of them. The finding—enabled by the Canadian Light Source (CLS) at the University of Saskatchewan—points to the possibility of one day treating disease by controlling the activity of harmful proteins.