Novel nanoparticle therapy using manganese could improve cancer treatment

A research team led by the University of Michigan College of Pharmacy and the University of Texas MD Anderson Cancer Center has developed a new type of nanoparticle therapy that could make cancer immunotherapy safer and more effective. The researchers say they've created a promising new treatment called CRYSTAL, short for Crystal-like STING-Activating nanoassemblies, by engineering a new nanoparticle that moves through the blood safely to target tumors but without triggering inflammation, which can lead to a range of negative side effects.