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Immunoglobulin G's overlooked hinge turns out to be a structural control hub
- January 30, 2026 at 6:11 PM
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The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo. Deleting a single amino acid in this region transforms a full-length antibody into a stable half-IgG1 molecule with altered immune activity.
Originally published at Phys.org