Monday, June 29, 2026
Science

DNA-binding protein blocks virulence cascade in a diarrhea pathogen outside hosts, study finds

Some pathogens use temperature as a trigger and activate virulence only after entering the warmer environment of a host. A research team from Ruhr University Bochum, Germany, and the University of Münster, Germany, investigated how a diarrheal pathogen suppresses its virulence outside of the human b...

DNA-binding protein blocks virulence cascade in a diarrhea pathogen outside hosts, study finds
Image: Phys.org
Some pathogens use temperature as a trigger and activate virulence only after entering the warmer environment of a host. A research team from Ruhr University Bochum, Germany, and the University of Münster, Germany, investigated how a diarrheal pathogen suppresses its virulence outside of the human body. Their study focused on the DNA-binding protein Fis, which is more abundant at cooler ambient temperatures of about 25°C.

Originally published at Phys.org

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