Flux pathway reveals why mussel-like liquid phase separation can happen in seconds

Have you ever wondered how mussels instantly glue themselves to rocks, allowing them to survive the crushing force of ocean waves? They complete this process in under 30 seconds. Yet, in a laboratory, replicating this process of molecular self-assembly, known as liquid-liquid phase separation (LLPS), typically takes dozens of minutes, if not hours. A research team of The Hong Kong University of Science and Technology (HKUST) has recently solved this long-standing puzzle using large-scale molecular dynamics simulation and theoretical analysis, revealing the secret to nature's incredible speed and providing implications for instant biocompatible surgical glues.