Tuesday, June 30, 2026
Science

Revolving doors and efficient engines: How proteins escape a molecular tangle

Trying to untangle a knot in a mess of strings can be frustrating and time-consuming. But not so for molecular machines—molecules that convert chemical energy into mechanical work and motion. Machines from the AAA+ family, which exist in the cells of all living organisms from bacteria to humans, can...

Revolving doors and efficient engines: How proteins escape a molecular tangle
Image: Phys.org
Trying to untangle a knot in a mess of strings can be frustrating and time-consuming. But not so for molecular machines—molecules that convert chemical energy into mechanical work and motion. Machines from the AAA+ family, which exist in the cells of all living organisms from bacteria to humans, can, among their many functions, recognize misfolded protein chains and swiftly unravel them.

Originally published at Phys.org

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