Chromatin tracking reveals two motion modes that help control gene expression

Gene expression is controlled, in part, by the interactions between genes and regulatory elements located along the genome. Those interactions depend on the ability of chromatin—a mix of DNA and proteins—to move around within a crowded space. In a new study, MIT researchers have measured chromatin movement at timescales ranging from hundreds of microseconds to hours, allowing them to rigorously quantify those dynamics for the first time.