DNA assembly insights could streamline design and manufacturing of nanostructures for medicine, materials and more

Researchers at The University of Texas at Austin have uncovered key principles that govern how DNA "origami" structures fold, findings that could make nanoscale materials faster and easier to manufacture. DNA origami is a technique that uses strands of DNA to self-assemble into tiny, programmable shapes. Although the method has shown promise for applications ranging from drug delivery to advanced materials, scientists have struggled to consistently achieve high yields, especially as structures become more complex.