One drug, two cleanup crews: A built-in backup for targeted protein degradation
Most drugs work by inhibition: they block a protein's activity but leave the protein itself intact. Targeted protein degradation takes a fundamentally different approach, harnessing the cell's own quality-control machinery to remove proteins entirely.
Image: Phys.org
Most drugs work by inhibition: they block a protein's activity but leave the protein itself intact. Targeted protein degradation takes a fundamentally different approach, harnessing the cell's own quality-control machinery to remove proteins entirely.
Originally published at Phys.org
