Thursday, August 6, 2026
Science

First metabolically activated molecular glue degrader may target cancer cells under oxidative stress

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates. The platform could help drug developers dramatically expand the range of disease-related proteins that can be therapeutically...

First metabolically activated molecular glue degrader may target cancer cells under oxidative stress
Image: Phys.org
Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates. The platform could help drug developers dramatically expand the range of disease-related proteins that can be therapeutically targeted for elimination via protein degradation.

Originally published at Phys.org

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