Scientists uncover a hidden mechanism that drives RNA synthesis
Scientists have long been fascinated by two promising classes of antibiotics that disable RNA polymerase (RNAP). They knew that these drugs could grind gene expression to a halt in several pathogens, including the bacterium behind tuberculosis, by binding to specific locations in RNAP. But despite d...
Image: Phys.org
Scientists have long been fascinated by two promising classes of antibiotics that disable RNA polymerase (RNAP). They knew that these drugs could grind gene expression to a halt in several pathogens, including the bacterium behind tuberculosis, by binding to specific locations in RNAP. But despite decades of study, a key question remained: What process are the drugs actually targeting?
Originally published at Phys.org
