Molecular architecture determines tomato plant resistance to its main pest

An international study investigating why wild tomatoes are more resistant to the tomato leafminer (Phthorimaea absoluta) than cultivated varieties revealed that the secret lies in the spatial structure of a plant defense molecule. The researchers mapped the biochemical origin of this difference and demonstrated that altering four amino acids in a single enzyme is sufficient to alter the structure of the substance and increase its toxicity against the pest. This finding paves the way for creating resistant tomatoes through gene editing.