Trehalose analog provides a new platform for designing water-soluble glycopolymers

Sugars are attractive building blocks for functional materials because of their high water affinity and diverse biological properties. Incorporating sugars into synthetic polymers can therefore provide materials that combine the processability of polymers with characteristics derived from carbohydrates. However, selective chemical modification of sugars is often challenging because they contain multiple hydroxyl groups with similar reactivities, making it difficult to introduce a polymerizable group at one defined position without multistep synthetic procedures.