Tuesday, July 28, 2026
Science

3′UTR-derived small RNA couples acid resistance to metabolic reprogramming in Salmonella within macrophages

Acid resistance is a crucial property that enterobacteria must possess to withstand host acidic environments during infection, including the gastrointestinal tract and macrophage phagosomes. The facultative intracellular pathogen Salmonella expresses the arginine decarboxylase AdiA, which confers ac...

3′UTR-derived small RNA couples acid resistance to metabolic reprogramming in Salmonella within macrophages
Image: Phys.org
Acid resistance is a crucial property that enterobacteria must possess to withstand host acidic environments during infection, including the gastrointestinal tract and macrophage phagosomes. The facultative intracellular pathogen Salmonella expresses the arginine decarboxylase AdiA, which confers acid resistance by catalyzing an H+-consuming reaction.

Originally published at Phys.org

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