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The key to attacking 'undruggable' proteins: Transient clustering state reveals a moving target
- March 3, 2026 at 9:40 PM
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Intrinsically disordered proteins lack a fixed structure, which is why they have been considered "undruggable" targets for drug development for years. However, these proteins play a key role in numerous diseases—ranging from various types of cancer to neurodegenerative disorders—long limiting the therapeutic options available to treat them.
Originally published at Phys.org